Please click the links below to access our updated interactive product guides. National coverage determinations ncd medicare regulations allow the center for medicare and medicaid services cms to develop coverage policies for medicarecovered tests and procedures. Advia centaurxp immunoassay system 12 advia centaur xp operators guide. Vista 1500 intelligent lab systems, advia centaur xp system, and. Advia centaur advia centaur xp immunoassay systems. Citation method subjects tsh lower limit miul tsh upper limit miul subject selection. Reference intervals for thyroid hormones on advia centaur.
The siemens advia centaur xp immunoassay system is a comprehensive diagnostic testing covers screening, diagnosis, risk assessment and monitoring with a capacity of 30 onboard reagents to maximize test capacity. The highperformance advia centaur xp system has more onboard reagents and dedicated stat capabilities to maximize productivity, regardless of volume or types of tests. Chemiluminescence is a chemical reaction that emits energy in the form of light. These coverage policies, called ncds, provide definitive guidance to providers concerning the medical necessity requirements of a particular test or procedure. Ad via centaur and advia centaur xp systems antihbs2 ahbs2 assay for the detection of antibodies to hepatitis b surface antigen assay summary sample type serum, plasma edta, lithiumheparinized, or sodiumheparinized sample volume 100 pl calibrator ahbs2 assay range 3. Previous studies using individual samples and standard materi. This observation impacts customers who use the tniultra assay on both the advia centaur cp and advia centaur advia centaur xp advia centaur xpt systems interchangeably when interpreting serial testing in patient samples. Advia centaur xp immunoassay system the highperformance advia centaur xp system has more onboard reagents and dedicated stat capabilities to maximize productivity, regardless of volume or types of tests.
Page 2 if the system is used in a manner not specified by siemens, the protection provided by the equipment may be impaired. The advia chemistry system is manufactured in japan for siemens. The update will clarify the utility of the psa assay. Characteristics advia centaur xp architect i2000sr elecsys e170 unicel dxi 800 method principle chemiluminescence immunoassay clia chemiluminescent microparticle immunoassay cmia electrochemiluminescence immunoassay eclia chemiluminescence immunoassay clia. Brahms pct tm and all other trademarks are the property of thermo fisher scientific inc. Performance evaluation of the high sensitivity cardiac. It retains most of the structural and functional characteristics of the. This observation impacts customers who use the tniultra assay on both the advia centaur cp and advia centauradvia centaur xpadvia centaur xpt systems interchangeably when interpreting serial testing in patient samples. Thyroidstimulating hormone and free thyroxine on the.
Important define container types for use on either the universal rack handler las or the onboard sample tray stt. The tsh3ul assay is based upon a twosite sandwich principle and the ft4 test is a competitive immunoassay. Advia labcell configuration with connected siemens analyzers in use in our laboratory at the time of the study in november 2014, reflecting replacement of two advia centaur xp immunoassay systems with two advia centaur xpt immunoassay systems in 2015. Advia centaur cp immunoassay system, adviacentaurcp. Advia centaur xp immunoassay system family healthcare associates testimonial siemens efficiency. Assay for the detection of hiv p24 antigen and antibodies to human. Siemens is actively pursuing the cause of this issue. Universal sample rack design eliminates manual tasks. User manuals, guides and specifications for your siemens advia centaur xp laboratory equipment. Advia centaur and advia centaur xp assay manual yumpu. With a high throughput of up to 240 tests per hour, the advia centaur xp immunoassay system keeps pace. Hbsag ad and ay is coupled to magnetic latex particles in the.
This test has been authorized only for the diagnosis for zika virus infection and not. Siemens advia centaur xp manuals and user guides, laboratory. Advia centau r is a registered and protected trademark belonging to siemens healthcare diagnostics. The communications protocol used by the advia centaur system is an open, nonproprietary. Citation method subjects tsh lower limit miul tsh upper. Advia centaur immunoassay systems global test menu advia centaur xp immunoassay system the highperformance advia centaur xp system has more onboard reagents and dedicated stat capabilities to maximize productivity, regardless of volume or types of tests. When used in combination with immunoassay technology, the light produced by the reaction indicates the amount of analyte in a sample.
Vogeser et al adviacentaur tsh3 assay 333 in the dilution experiments, linearity of the tsh results was demonstrated in the studied range up to 91 mul through a correlation coefficient of 0. It is for use with the advia centaurxp and advia centaur cp. Chemiluminescent assay clia for the determination of procalcitonin pct in human serum and plasma on the advia centaur xp and advia centaur cp random access analysers siemens. Thyroidstimulating hormone and free thyroxine on the advia centaur immunoassay. Consumers and health professionals are advised that siemens healthcare diagnostics, in consultation with the tga, is in the process of updating the instructions for use ifu for prostatespecific antigen psa assays used with advia centaur systems. Always ready, continuous operation without interruption. An analytical evaluation of the thyroid stimulating hormone tsh3 assay on the bayer advia centaur immunoassay system was performed. The advia centaur cp immunoassay system is a surprisingly powerful and fast midsized immunoassay system. Meet the growing needs of your lab in less time from advia centaur xp immunoassay analyzer. The siemens advia centaur xp immunoassay system is a comprehensive diagnostic testing covers screening, diagnosis, risk assessment and monitoring with a capacity of 30 onboard reagents to maximize test capacity with a high throughput of up to 240 tests per hour, the advia centaur xp immunoassay system keeps pace with peak workload times. Immunoassay system advia centaur xp, immunoassaysystem. The assay principle combines a sandwich immunoassay with the detection of light emission as the final step. Advia centaur xpt system has improved over the previous system evaluate benefits of the new user software compare qc results for the assays methods the new advia centaur xpt immunoassay system represents a technological advance over the previous advia centaur xp model.
Youll also learn about additional concepts including calibration, quality control, maintenance and troubleshooting. Enhanced productivity to meet peak workloads with optimal sample processing and a high level of efficiency. For the advia centaur system to communicate with a laboratory information system lis, both systems must conform to the same threelayered protocol. Psa assay used with advia centaur systems therapeutic goods. Advia centaur xp instrument which was maintained as per the manufacturer standards with no signi.
Highperformance advia centaur xp system has more onboard reagents and dedicated stat capabilities to maximize productivity, regardless of volume or types of tests. Architect i2000 advia centaur xp classic fse service training nilesh shah conducted hardware training on centaur xp classic at gurgaon traininig center. Allow to reach the controls room temperature before use. Can you maintain speed and accuracy for an increasingly diverse patient population. Communication protocol standards are defined for each layer. Complex psa using advia centaur in serum nhanes 20072008. The advia centaur xpt system delivers the results that clinicians depend upon for accurate diagnoses and better patient careand does so predictably and consistently. The proteolytic activity of psa is inhibited in the bloodstream by the formation of complexes with serine protease inhibitors. Assay and ise precision analysis comparing advia chemistry. L of sample into a cuvette, and incubates for 6 minutes at 37c. Mar 22, 2016 recommended controls are advia testpoint haematology controls low, normal and high that should be keep and store at 25 degree c.
Siemens unites innovative workflow solutions with clinical excellence in the advia centaur xpt system, leading to greater laboratory productivity to stay ahead of increasing w. Assay and ise precision analysis comparing advia chemistry xpt system with advia 1800 clinical chemistry system. Comparison of four automated carcinoembryonic antigen. The highperformance advia centaur xp system has more onboard reagents. Workflow and efficiency advantages of the new advia centaur xpt. Brahms pct tm and all other trademarks are the property of. Recommended controls are advia testpoint haematology controls low, normal and high that should be keep and store at 25 degree c. General analytical requirements linearity, resistance to typical interferences, absence of a carryover effect were fulfilled and reproducibility was satisfactory. Anatomic pathology computer systems bedside glucose testing systems billingaccounts receivablercm systems chemistry and immunoassay analyzers for poc and lowvolume labs chemistry and immunoassay analyzers, mid and highvolume labs coagulation analyzers hematology analyzers laboratory information systems. Performance evaluation of the high sensitivity cardiac troponin i assay on the advia centaur xp xpt immunoassay systems payne rc1, halik l1, dipasquale c1, ma j1, zhang h1, zhang j1, conklin j1, may e1, foltz m2, howell r1, evans d1, yokoyama k1, natrajan a3, bahrainy y1, lei j1.
May 01, 2012 the results of the respective tumor marker levels as measured by dxi were compared with afp, cea, and ca 125 levels measured by the advia centaur xp immunoassay system centaur siemens healthcare diagnostics inc. The advia centaur xp system is an automated, immunoassay analyzer that offers optimal productivity and efficiency. Performance evaluation of the ntprobnp assay using acridinium ester technology on the advia centaur xp immunoassay system schiavoni l, amin a, larson l, privon g, schafenberg d, squittiere a, whalen j, wilkins g. Psa assay used with advia centaur systems therapeutic. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life. Run controls at the start of the patient workload, evaluate all controls before reporting patient results. Bayer healthcare llc, diagnostics division, has developed several new assays on the advia centaur immunoassay system for the detection of markers of hepatitis b virus infection in human serum and. Performance evaluation of the ntprobnp assay using.
The fourth edition of the immunoassay handbook provides an excellent, thoroughly updated guide to the science, technology and applications of elisa and other immunoassays, including a wealth of practical advice. Advia centaur xp reference manual free ebook download as pdf file. Sample carryover eliminated by consumable advia centaur pipette tips pipette tips advia centaur type, 480 onboard, automatic tracking and flagging of inventory bar codes formats supported code 128, code 39, codabar, interleaved 2 of 5 any or all symbologies may be active at one time reagents and reagent handling reagent cooling 10. With its broad menu and short turn around times tat, you can do more without compromising efficiency, productivity, or quality. Prostate specific antigen psa is a serine protease produced by epithelial cells of the prostate gland. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary. The elf test is indicated, in conjunction with other laboratory findings and clinical assessments, as an aid in the diagnosis and assessment of the severity of liver fibrosis in.
Ad via centaur and advia centaur xp systems antihbs2 ahbs2. Advia centaur xp reference manual immunoassay computing. When you use the same sample rack on the rack handler and on an advia centaur system, select allowable tube sizes from the table below. In this online training program, youll learn about the components of the instrument, navigate the software and routine operation. Can your lab handle both routine and specialized testing without sacrificing efficiency. The advia centaur zika test has not been fda cleared or approved. Advia centaur tsh indications for use describe for in vitro diagnostic use in the quantitative determination of thyroidstimulating hormone tsh, thyrotropin in serum using the advia centaur, advia centaur xp and advia centaur xpt systems. The advia centaur and advia centaur xp systems automatically perform the following steps. A multicenter assessment of analytical performance. The advia centaur xp assays use acridinium ester ae as the.
The advia centaur cp immunoassay system is a midvolume, highthroughput bench top system that enhances your inhouse test capability. Advia centaur laboratory equipment pdf manual download. Assay principle the advia centaur antihbs2 assay is a sandwich immunoassay using direct, chemiluminometric technology. Database contains 1 siemens advia centaur xp manuals available for free online viewing or downloading in pdf. View and download siemens advia centaur safety notes online. Advia centaur xp, architect i2000sr, elecsys e170, and unicel dxi800.
Xpt immunoassay system, are designed to enable continuous and simple operation, facilitate delivery of high quality, rapid results, and work seamlessly with automation in highvolume laboratories. It is for use with the advia centaurxp and advia centaur cp analysers. Advia centaur and advia centaur xp assay manual insulin 1 10. This test has been authorized by fda under an eua for use by authorized laboratories. Performance of hepatitis b assays on the bayer advia.